PCSK9 variation and association with blood pressure in African Americans: preliminary findings from the HyperGEN and REGARDS studies

Proprotein convertase subtilisin/kexin type 9 (encoded by PCSK9) plays a well-known role in the regulation of low-density lipoprotein (LDL) receptors, and an inhibitor of this enzyme is a promising new therapeutic for hyperlipidemia. Recently, animal and human studies also implicate PCSK9 genetic va...

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Gepubliceerd in:Front Genet
Hoofdauteurs: Tran, Ngan T., Aslibekyan, Stella, Tiwari, Hemant K., Zhi, Degui, Sung, Yun Ju, Hunt, Steven C., Rao, DC, Broeckel, Ulrich, Judd, Suzanne E., Muntner, Paul, Kent, Shia T., Arnett, Donna K., Irvin, Marguerite R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2015
Onderwerpen:
Pharmacology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4389541/
https://ncbi.nlm.nih.gov/pubmed/25904937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2015.00136
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