PCSK9 variation and association with blood pressure in African Americans: preliminary findings from the HyperGEN and REGARDS studies

Proprotein convertase subtilisin/kexin type 9 (encoded by PCSK9) plays a well-known role in the regulation of low-density lipoprotein (LDL) receptors, and an inhibitor of this enzyme is a promising new therapeutic for hyperlipidemia. Recently, animal and human studies also implicate PCSK9 genetic va...

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Detalhes bibliográficos
Publicado no:Front Genet
Main Authors: Tran, Ngan T., Aslibekyan, Stella, Tiwari, Hemant K., Zhi, Degui, Sung, Yun Ju, Hunt, Steven C., Rao, DC, Broeckel, Ulrich, Judd, Suzanne E., Muntner, Paul, Kent, Shia T., Arnett, Donna K., Irvin, Marguerite R.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4389541/
https://ncbi.nlm.nih.gov/pubmed/25904937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2015.00136
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