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The soluble CTLA-4 receptor and its role in autoimmune diseases: an update

CTLA-4, initially described as a membranebound molecule, is a costimulatory receptor transducing a potent inhibitory signal. Increasing evidence shows the CTLA-4 gene to be an important susceptibility locus for autoimmune endocrinopathies and other autoimmune disorders. A soluble form of cytotoxic T...

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Bibliografiske detaljer
Udgivet i:Auto Immun Highlights
Main Authors: Saverino, Daniele, Simone, Rita, Bagnasco, Marcello, Pesce, Giampaola
Format: Artigo
Sprog:Inglês
Udgivet: Springer International Publishing 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4389044/
https://ncbi.nlm.nih.gov/pubmed/26000110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13317-010-0011-7
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