Tumor necrosis factor alpha inhibits signaling from the insulin receptor.

Insulin resistance is a common problem associated with infections and cancer and, most importantly, is the central component of non-insulin-dependent diabetes mellitus. We have recently shown that tumor necrosis factor (TNF) alpha is a key mediator of insulin resistance in animal models of non-insul...

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Главные авторы: Hotamisligil, G S, Murray, D L, Choy, L N, Spiegelman, B M
Формат: Artigo
Язык:Inglês
Опубликовано: 1994
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC43887/
https://ncbi.nlm.nih.gov/pubmed/8197147
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