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TAp63γ and ΔNp63β Promote Osteoblastic Differentiation of Human Mesenchymal Stem Cells: Regulation by Vitamin D3 Metabolites

The transcription factor p63 is required for skeletal formation, and is important for the regulation of 1α,25(OH)(2)D(3) receptor (VDR) in human mesenchymal stem cells (hMSC). Herein we report that TAp63γ and ΔNp63β appear to be an integral part of the osteoblastic differentiation of hMSC and are di...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Curtis, Kevin M., Aenlle, Kristina K., Frisch, Rachel N., Howard, Guy A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4388628/
https://ncbi.nlm.nih.gov/pubmed/25849854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0123642
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