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Probing ADAMTS13 Substrate Specificity using Phage Display

Von Willebrand factor (VWF) is a large, multimeric protein that regulates hemostasis by tethering platelets to the subendothelial matrix at sites of vascular damage. The procoagulant activity of plasma VWF correlates with the length of VWF multimers, which is proteolytically controlled by the metall...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Desch, Karl C., Kretz, Colin, Yee, Andrew, Gildersleeve, Robert, Metzger, Kristin, Agrawal, Nidhi, Cheng, Jane, Ginsburg, David
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4388381/
https://ncbi.nlm.nih.gov/pubmed/25849793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0122931
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