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Myeloperoxidase scavenges peroxynitrite: A novel anti-inflammatory action of the heme enzyme

Peroxynitrite, a potent pro-inflammatory and cytotoxic species, interacts with a variety of heme containing proteins. We addressed the question whether (i) the interaction of myeloperoxidase (MPO, an enzyme generating hypochlorous acid from hydrogen peroxide and chloride ions) with peroxynitrite aff...

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Bibliographic Details
Published in:Arch Biochem Biophys
Main Authors: Koyani, Chintan N., Flemmig, Joerg, Malle, Ernst, Arnhold, Juergen
Format: Artigo
Language:Inglês
Published: Academic Press 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4388333/
https://ncbi.nlm.nih.gov/pubmed/25731855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2015.02.028
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