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Structure of dihydrodipicolinate synthase from the commensal bacterium Bacteroides thetaiotaomicron at 2.1 Å resolution

Dihydrodipicolinate synthase (DapA) catalyzes the first committed step of the diaminopimelate biosynthetic pathway of lysine. It has been shown to be an essential enzyme in many bacteria and has been the subject of research to generate novel antibiotics. However, this pathway is present in both path...

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書目詳細資料
發表在:Acta Crystallogr F Struct Biol Commun
Main Authors: Mank, Nicholas, Arnette, Amy, Klapper, Vince, Offermann, Lesa, Chruszcz, Maksymilian
格式: Artigo
語言:Inglês
出版: International Union of Crystallography 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4388182/
https://ncbi.nlm.nih.gov/pubmed/25849508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X15004628
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