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Structure of dihydrodipicolinate synthase from the commensal bacterium Bacteroides thetaiotaomicron at 2.1 Å resolution

Dihydrodipicolinate synthase (DapA) catalyzes the first committed step of the diaminopimelate biosynthetic pathway of lysine. It has been shown to be an essential enzyme in many bacteria and has been the subject of research to generate novel antibiotics. However, this pathway is present in both path...

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Bibliografiske detaljer
Udgivet i:Acta Crystallogr F Struct Biol Commun
Main Authors: Mank, Nicholas, Arnette, Amy, Klapper, Vince, Offermann, Lesa, Chruszcz, Maksymilian
Format: Artigo
Sprog:Inglês
Udgivet: International Union of Crystallography 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4388182/
https://ncbi.nlm.nih.gov/pubmed/25849508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X15004628
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