Comparative proteomic analyses demonstrate enhanced interferon and STAT-1 activation in reovirus T3D-infected HeLa cells

As obligate intracellular parasites, viruses are exclusively and intimately dependent upon their host cells for replication. During replication viruses induce profound changes within cells, including: induction of signaling pathways, morphological changes, and cell death. Many such cellular perturba...

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Bibliographic Details
Published in:Front Cell Infect Microbiol
Main Authors: Ezzati, Peyman, Komher, Krysten, Severini, Giulia, Coombs, Kevin M.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2015
Subjects:
Microbiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4388007/
https://ncbi.nlm.nih.gov/pubmed/25905045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2015.00030
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