Differential Effects of IL-17A and TNF-α on Osteoblastic Differentiation of Isolated Synoviocytes and on Bone Explants from Arthritis Patients

OBJECTIVE: TNF-α and IL-17A act on fibroblast-like synoviocytes (FLS) and contribute to cytokine production, inflammation, and tissue destruction in rheumatoid arthritis (RA). The aim of this study was to compare their effects on osteogenic differentiation of isolated FLS and on whole bone explants...

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Bibliografski detalji
Izdano u:Front Immunol
Glavni autori: Osta, Bilal, Roux, Jean-Paul, Lavocat, Fabien, Pierre, Marlène, Ndongo-Thiam, Ndieme, Boivin, Georges, Miossec, Pierre
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2015
Teme:
Immunology
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4387961/
https://ncbi.nlm.nih.gov/pubmed/25904914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2015.00151
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