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Conditional knockout of smooth muscle sodium calcium exchanger type‐1 lowers blood pressure and attenuates Angiotensin II‐salt hypertension

The functions of smooth muscle sodium calcium exchanger (NCX) in the vasculature are controversial and poorly understood. To determine the possible roles of NCX in the vascular phenotype and function, we developed a novel mouse model (SM‐NCX1 KO) in which the smooth muscle‐specific NCX type‐1 (NCX1)...

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Bibliografske podrobnosti
izdano v:Physiol Rep
Main Authors: Wang, Youhua, Chen, Ling, Li, Meng, Cha, Helen, Iwamoto, Takahiro, Zhang, Jin
Format: Artigo
Jezik:Inglês
Izdano: Wiley Periodicals, Inc. 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4387742/
https://ncbi.nlm.nih.gov/pubmed/25626872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.12273
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