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Conditional knockout of smooth muscle sodium calcium exchanger type‐1 lowers blood pressure and attenuates Angiotensin II‐salt hypertension

The functions of smooth muscle sodium calcium exchanger (NCX) in the vasculature are controversial and poorly understood. To determine the possible roles of NCX in the vascular phenotype and function, we developed a novel mouse model (SM‐NCX1 KO) in which the smooth muscle‐specific NCX type‐1 (NCX1)...

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Detalhes bibliográficos
Publicado no:Physiol Rep
Main Authors: Wang, Youhua, Chen, Ling, Li, Meng, Cha, Helen, Iwamoto, Takahiro, Zhang, Jin
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Periodicals, Inc. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4387742/
https://ncbi.nlm.nih.gov/pubmed/25626872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.12273
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