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STING, nanoparticles, autoimmune disease and cancer: a novel paradigm for immunotherapy?
DNA has potent immunogenic properties that are useful to enhance vaccine efficacy. DNA also incites hyper-inflammation and autoimmunity if DNA sensing is not regulated. Paradoxically, DNA regulates immunity and autoimmunity when administered systemically as DNA nanoparticles (DNPs). DNPs regulated i...
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| Vydáno v: | Expert Rev Clin Immunol |
|---|---|
| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2014
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4387570/ https://ncbi.nlm.nih.gov/pubmed/25521938 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1586/1744666X.2015.995097 |
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