cMyc-mediated activation of serine biosynthesis pathway is critical for cancer progression under nutrient deprivation conditions

Cancer cells are known to undergo metabolic reprogramming to sustain survival and rapid proliferation, however, it remains to be fully elucidated how oncogenic lesions coordinate the metabolic switch under various stressed conditions. Here we show that deprivation of glucose or glutamine, two major...

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Detalhes bibliográficos
Publicado no:Cell Res
Main Authors: Sun, Linchong, Song, Libing, Wan, Qianfen, Wu, Gongwei, Li, Xinghua, Wang, Yinghui, Wang, Jin, Liu, Zhaoji, Zhong, Xiuying, He, Xiaoping, Shen, Shengqi, Pan, Xin, Li, Ailing, Wang, Yulan, Gao, Ping, Tang, Huiru, Zhang, Huafeng
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4387561/
https://ncbi.nlm.nih.gov/pubmed/25793315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2015.33
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