Menin enhances c-Myc-mediated transcription to promote cancer progression

Menin is an enigmatic protein that displays unique ability to either suppress or promote tumorigenesis in a context-dependent manner. The role for Menin to promote oncogenic functions has been largely attributed to its essential role in forming the MLL methyltransferase complex, which mediates H3K4m...

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發表在:Nat Commun
Main Authors: Wu, Gongwei, Yuan, Mengqiu, Shen, Shengqi, Ma, Xiaoyu, Fang, Jingwen, Zhu, Lianbang, Sun, Linchong, Liu, Zhaoji, He, Xiaoping, Huang, De, Li, Tingting, Li, Chenchen, Wu, Jun, Hu, Xin, Li, Zhaoyong, Song, Libing, Qu, Kun, Zhang, Huafeng, Gao, Ping
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2017
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5424160/
https://ncbi.nlm.nih.gov/pubmed/28474697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15278
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