miR-27b synergizes with anticancer drugs via p53 activation and CYP1B1 suppression

Liver and kidney cancers are notorious for drug resistance. Due to the complexity, redundancy and interpatient heterogeneity of resistance mechanisms, most efforts targeting a single pathway were unsuccessful. Novel personalized therapies targeting multiple essential drug resistance pathways in para...

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Vydáno v:Cell Res
Hlavní autoři: Mu, Wenjing, Hu, Chaobo, Zhang, Haibin, Qu, Zengqiang, Cen, Jin, Qiu, Zhixin, Li, Chao, Ren, Haozhen, Li, Yixue, He, Xianghuo, Shi, Xiaolei, Hui, Lijian
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2015
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4387554/
https://ncbi.nlm.nih.gov/pubmed/25698578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2015.23
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