Genome-wide Association Study of Virologic Response with Efavirenz- or Abacavir-containing Regimens in AIDS Clinical Trials Group Protocols

BACKGROUND: Efavirenz and abacavir are components of recommended first-line regimens for human immunodeficiency virus (HIV)-1 infection. We used genome-wide genotyping and clinical data to explore genetic associations with virologic failure among subjects randomized to efavirenz- or abacavir-contain...

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Gepubliceerd in:Pharmacogenet Genomics
Hoofdauteurs: Lehmann, David S., Ribaudo, Heather J., Daar, Eric S., Gulick, Roy M., Haubrich, Richard H., Robbins, Gregory K., de Bakker, Paul I.W., Haas, David W., McLaren, Paul J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4387236/
https://ncbi.nlm.nih.gov/pubmed/25461247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0000000000000106
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