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Nfkb1 Activation by the E26 Transformation-Specific Transcription Factors PU.1 and Spi-B Promotes Toll-Like Receptor-Mediated Splenic B Cell Proliferation

Generation of antibodies against T-independent and T-dependent antigens requires Toll-like receptor (TLR) engagement on B cells for efficient responses. However, the regulation of TLR expression and responses in B cells is not well understood. PU.1 and Spi-B (encoded by Sfpi1 and Spib, respectively)...

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Bibliografische gegevens
Gepubliceerd in:Mol Cell Biol
Hoofdauteurs: Li, Stephen K. H., Abbas, Ali K., Solomon, Lauren A., Groux, Gaëlle M. N., DeKoter, Rodney P.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4387210/
https://ncbi.nlm.nih.gov/pubmed/25733685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00117-15
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