DACH1, a Zona Glomerulosa Selective Gene in the Human Adrenal, Activates Transforming Growth Factor-β Signaling and Suppresses Aldosterone Secretion

Common somatic mutations in CACNAID and ATP1A1 may define a subgroup of smaller, zona glomerulosa (ZG)–like aldosterone-producing adenomas. We have therefore sought signature ZG genes, which may provide insight into the frequency and pathogenesis of ZG-like aldosterone-producing adenomas. Twenty-one...

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Vydáno v:Hypertension
Hlavní autoři: Zhou, Junhua, Shaikh, Lalarukh Haris, Neogi, Sudeshna G., McFarlane, Ian, Zhao, Wanfeng, Figg, Nichola, Brighton, Cheryl A., Maniero, Carmela, Teo, Ada E.D., Azizan, Elena A. B., Brown, Morris J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Lippincott, Williams & Wilkins 2015
Témata:
Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4387203/
https://ncbi.nlm.nih.gov/pubmed/25776071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYP.0000000000000025
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