Activation of protein phosphatase 2A tumor suppressor as potential treatment of pancreatic cancer

We utilized three tiers of screening to identify novel therapeutic agents for pancreatic cancers. First, we analyzed 14 pancreatic cancer cell lines against a panel of 66 small‐molecule kinase inhibitors and dasatinib was the most potent. Second, we performed RNA expression analysis on 3 dasatinib‐r...

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發表在:Mol Oncol
Main Authors: Chien, Wenwen, Sun, Qiao-Yang, Lee, Kian Leong, Ding, Ling-Wen, Wuensche, Peer, Torres-Fernandez, Lucia A., Tan, Siew Zhuan, Tokatly, Itay, Zaiden, Norazean, Poellinger, Lorenz, Mori, Seiichi, Yang, Henry, Tyner, Jeffrey W., Koeffler, H. Phillip
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2015
主題:
Research Articles
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4387089/
https://ncbi.nlm.nih.gov/pubmed/25637283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2015.01.002
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