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The role of hexokinase in cardioprotection – mechanism and potential for translation
Mitochondrial permeability transition pore (mPTP) opening plays a critical role in cardiac reperfusion injury and its prevention is cardioprotective. Tumour cell mitochondria usually have high levels of hexokinase isoform 2 (HK2) bound to their outer mitochondrial membranes (OMM) and HK2 binding to...
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| Vydáno v: | Br J Pharmacol |
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| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
John Wiley and Sons Inc.
2015
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4386983/ https://ncbi.nlm.nih.gov/pubmed/25204670 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12899 |
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