Poly(lactic-co-glycolic acid) nanoparticles conjugated with CD133 aptamers for targeted salinomycin delivery to CD133(+) osteosarcoma cancer stem cells

BACKGROUND: Cancer stem cells (CSCs) possess the characteristics associated with normal stem cells and are responsible for cancer initiation, recurrence, and metastasis. CD133 is regarded as a CSCs marker of osteosarcoma, which is the most common primary bone malignancy in childhood and adolescence....

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Vydáno v:Int J Nanomedicine
Hlavní autoři: Ni, Miaozhong, Xiong, Min, Zhang, Xinchao, Cai, Guoping, Chen, Huaiwen, Zeng, Qingmin, Yu, Zuochong
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2015
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4386781/
https://ncbi.nlm.nih.gov/pubmed/25848270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S78498
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