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Interaction between endoplasmic/sarcoplasmic reticulum stress (ER/SR stress), mitochondrial signaling and Ca(2+) regulation in airway smooth muscle (ASM)

Airway inflammation is a key aspect of diseases such as asthma. Several inflammatory cytokines (e.g., TNFα and IL-13) increase cytosolic Ca(2+) ([Ca(2+)](cyt)) responses to agonist stimulation and Ca(2+) sensitivity of force generation, thereby enhancing airway smooth muscle (ASM) contractility (hyp...

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Detalhes bibliográficos
Publicado no:Can J Physiol Pharmacol
Main Authors: Delmotte, Philippe, Sieck, Gary C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4386727/
https://ncbi.nlm.nih.gov/pubmed/25506723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1139/cjpp-2014-0361
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