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TNFα selectively activates the IRE1α/XBP1 endoplasmic reticulum stress pathway in human airway smooth muscle cells

Airway inflammation is a key aspect of diseases such as asthma. Proinflammatory cytokines such as TNFα mediate the inflammatory response. In various diseases, inflammation leads to endoplasmic reticulum (ER) stress, the accumulation of unfolded proteins, which triggers homeostatic responses to resto...

詳細記述

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書誌詳細
出版年:Am J Physiol Lung Cell Mol Physiol
主要な著者: Yap, John, Chen, Xujiao, Delmotte, Philippe, Sieck, Gary C.
フォーマット: Artigo
言語:Inglês
出版事項: American Physiological Society 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7099431/
https://ncbi.nlm.nih.gov/pubmed/31940218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00212.2019
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