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NLRP3 Inflammasome Contributes to Inflammation after Intracerebral Hemorrhage
OBJECTIVE: The NLRP3 (NALP3, cryopyrin) inflammasome, a key component of the innate immune system, facilitates caspase-1 and interleukin (IL)–1β processing, which amplifies the inflammatory response. Here, we investigated whether NLRP3 knockdown decreases neutrophil infiltration, reduces brain edema...
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| Udgivet i: | Ann Neurol |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4386653/ https://ncbi.nlm.nih.gov/pubmed/24273204 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.24070 |
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