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Towards an HIV-1 cure: measuring the latent reservoir

The latent reservoir of HIV-1 in resting memory CD4(+) T cells serves as a major barrier to curing HIV-1 infection. While many PCR- and culture-based assays have been used to measure the size of the latent reservoir, correlation between results of different assays is poor and recent studies indicate...

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Détails bibliographiques
Publié dans:Trends Microbiol
Auteurs principaux: Bruner, Katherine M., Hosmane, Nina N., Siliciano, Robert F.
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4386620/
https://ncbi.nlm.nih.gov/pubmed/25747663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tim.2015.01.013
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