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Inversion of Sonic hedgehog action on its canonical pathway by electrical activity
Sonic hedgehog (Shh) is a morphogenic protein that operates through the Gli transcription factor-dependent canonical pathway to orchestrate normal development of many tissues. Because aberrant levels of Gli activity lead to a wide spectrum of diseases ranging from neurodevelopmental defects to cance...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4386408/ https://ncbi.nlm.nih.gov/pubmed/25829542 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1419690112 |
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