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Sonic hedgehog signaling is decoded by calcium spike activity in the developing spinal cord
Evolutionarily conserved hedgehog proteins orchestrate the patterning of embryonic tissues, and dysfunctions in their signaling can lead to tumorigenesis. In vertebrates, Sonic hedgehog (Shh) is essential for nervous system development, but the mechanisms underlying its action remain unclear. Early...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2011
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3060219/ https://ncbi.nlm.nih.gov/pubmed/21368195 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1018217108 |
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