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Sonic hedgehog signaling is decoded by calcium spike activity in the developing spinal cord

Evolutionarily conserved hedgehog proteins orchestrate the patterning of embryonic tissues, and dysfunctions in their signaling can lead to tumorigenesis. In vertebrates, Sonic hedgehog (Shh) is essential for nervous system development, but the mechanisms underlying its action remain unclear. Early...

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Bibliografiset tiedot
Päätekijät: Belgacem, Yesser H., Borodinsky, Laura N.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3060219/
https://ncbi.nlm.nih.gov/pubmed/21368195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1018217108
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