Myosin VI regulates gene pairing and transcriptional pause release in T cells

Naive CD4 T cells differentiate into several effector lineages, which generate a stronger and more rapid response to previously encountered immunological challenges. Although effector function is a key feature of adaptive immunity, the molecular basis of this process is poorly understood. Here, we i...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Zorca, Cornelia E., Kim, Lark Kyun, Kim, Yoon Jung, Krause, Matthew R., Zenklusen, Daniel, Spilianakis, Charalampos G., Flavell, Richard A.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2015
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PNAS Plus
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4386387/
https://ncbi.nlm.nih.gov/pubmed/25770220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1502461112
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