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AIM2 and NLRC4 inflammasomes contribute with ASC to acute brain injury independently of NLRP3

Inflammation that contributes to acute cerebrovascular disease is driven by the proinflammatory cytokine interleukin-1 and is known to exacerbate resulting injury. The activity of interleukin-1 is regulated by multimolecular protein complexes called inflammasomes. There are multiple potential inflam...

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Podrobná bibliografie
Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Denes, Adam, Coutts, Graham, Lénárt, Nikolett, Cruickshank, Sheena M., Pelegrin, Pablo, Skinner, Joanne, Rothwell, Nancy, Allan, Stuart M., Brough, David
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4386342/
https://ncbi.nlm.nih.gov/pubmed/25775556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1419090112
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