Silencing of end-joining repair for efficient site-specific gene insertion after TALEN/CRISPR mutagenesis in Aedes aegypti

Conventional control strategies for mosquito-borne pathogens such as malaria and dengue are now being complemented by the development of transgenic mosquito strains reprogrammed to generate beneficial phenotypes such as conditional sterility or pathogen resistance. The widespread success of site-spe...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Basu, Sanjay, Aryan, Azadeh, Overcash, Justin M., Samuel, Glady Hazitha, Anderson, Michelle A. E., Dahlem, Timothy J., Myles, Kevin M., Adelman, Zach N.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2015
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4386333/
https://ncbi.nlm.nih.gov/pubmed/25775608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1502370112
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