Silencing of end-joining repair for efficient site-specific gene insertion after TALEN/CRISPR mutagenesis in Aedes aegypti

Conventional control strategies for mosquito-borne pathogens such as malaria and dengue are now being complemented by the development of transgenic mosquito strains reprogrammed to generate beneficial phenotypes such as conditional sterility or pathogen resistance. The widespread success of site-spe...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Basu, Sanjay, Aryan, Azadeh, Overcash, Justin M., Samuel, Glady Hazitha, Anderson, Michelle A. E., Dahlem, Timothy J., Myles, Kevin M., Adelman, Zach N.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2015
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4386333/
https://ncbi.nlm.nih.gov/pubmed/25775608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1502370112
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