Silencing of end-joining repair for efficient site-specific gene insertion after TALEN/CRISPR mutagenesis in Aedes aegypti

Conventional control strategies for mosquito-borne pathogens such as malaria and dengue are now being complemented by the development of transgenic mosquito strains reprogrammed to generate beneficial phenotypes such as conditional sterility or pathogen resistance. The widespread success of site-spe...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Proc Natl Acad Sci U S A
Κύριοι συγγραφείς: Basu, Sanjay, Aryan, Azadeh, Overcash, Justin M., Samuel, Glady Hazitha, Anderson, Michelle A. E., Dahlem, Timothy J., Myles, Kevin M., Adelman, Zach N.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: National Academy of Sciences 2015
Θέματα:
Biological Sciences
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4386333/
https://ncbi.nlm.nih.gov/pubmed/25775608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1502370112
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