Silencing of end-joining repair for efficient site-specific gene insertion after TALEN/CRISPR mutagenesis in Aedes aegypti

Conventional control strategies for mosquito-borne pathogens such as malaria and dengue are now being complemented by the development of transgenic mosquito strains reprogrammed to generate beneficial phenotypes such as conditional sterility or pathogen resistance. The widespread success of site-spe...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Basu, Sanjay, Aryan, Azadeh, Overcash, Justin M., Samuel, Glady Hazitha, Anderson, Michelle A. E., Dahlem, Timothy J., Myles, Kevin M., Adelman, Zach N.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2015
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4386333/
https://ncbi.nlm.nih.gov/pubmed/25775608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1502370112
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