Silencing of end-joining repair for efficient site-specific gene insertion after TALEN/CRISPR mutagenesis in Aedes aegypti

Conventional control strategies for mosquito-borne pathogens such as malaria and dengue are now being complemented by the development of transgenic mosquito strains reprogrammed to generate beneficial phenotypes such as conditional sterility or pathogen resistance. The widespread success of site-spe...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Basu, Sanjay, Aryan, Azadeh, Overcash, Justin M., Samuel, Glady Hazitha, Anderson, Michelle A. E., Dahlem, Timothy J., Myles, Kevin M., Adelman, Zach N.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4386333/
https://ncbi.nlm.nih.gov/pubmed/25775608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1502370112
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