IGF-2R-G(αq) signaling and cardiac hypertrophy in the low-birth-weight lamb

The cardiac insulin-like growth factor 2 receptor (IGF-2R) can induce cardiomyocyte hypertrophy in a heterotrimeric G protein receptor-coupled manner involving αq (G(αq)) or αs (G(αs)). We have previously shown increased left ventricular weight and cardiac IGF-2 and IGF-2R gene expression in low-bir...

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Detalhes bibliográficos
Publicado no:Am J Physiol Regul Integr Comp Physiol
Main Authors: Wang, Kimberley C. W., Tosh, Darran N., Zhang, Song, McMillen, I. Caroline, Duffield, Jaime A., Brooks, Doug A., Morrison, Janna L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2015
Assuntos:
Cardiovascular and Renal Integration
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4385999/
https://ncbi.nlm.nih.gov/pubmed/25632020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00346.2014
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