Long noncoding RNA lincRNA-p21 is the major mediator of UVB-induced and p53-dependent apoptosis in keratinocytes

LincRNA-p21 is a long noncoding RNA and a transcriptional target of p53 and HIF-1α. LincRNA-p21 regulates gene expression in cis and trans, mRNA translation, protein stability, the Warburg effect, and p53-dependent apoptosis and cell cycle arrest in doxorubicin-treated mouse embryo fibroblasts. p53...

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Publicat a:Cell Death Dis
Autors principals: Hall, J R, Messenger, Z J, Tam, H W, Phillips, S L, Recio, L, Smart, R C
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2015
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4385943/
https://ncbi.nlm.nih.gov/pubmed/25789975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.67
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