Variola virus F1L is a Bcl-2-like protein that unlike its vaccinia virus counterpart inhibits apoptosis independent of Bim

Subversion of host cell apoptosis is an important survival strategy for viruses to ensure their own proliferation and survival. Certain viruses express proteins homologous in sequence, structure and function to mammalian pro-survival B-cell lymphoma 2 (Bcl-2) proteins, which prevent rapid clearance...

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Bibliografiske detaljer
Udgivet i:Cell Death Dis
Main Authors: Marshall, B, Puthalakath, H, Caria, S, Chugh, S, Doerflinger, M, Colman, P M, Kvansakul, M
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2015
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4385930/
https://ncbi.nlm.nih.gov/pubmed/25766319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.52
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