Variola virus F1L is a Bcl-2-like protein that unlike its vaccinia virus counterpart inhibits apoptosis independent of Bim

Subversion of host cell apoptosis is an important survival strategy for viruses to ensure their own proliferation and survival. Certain viruses express proteins homologous in sequence, structure and function to mammalian pro-survival B-cell lymphoma 2 (Bcl-2) proteins, which prevent rapid clearance...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Marshall, B, Puthalakath, H, Caria, S, Chugh, S, Doerflinger, M, Colman, P M, Kvansakul, M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4385930/
https://ncbi.nlm.nih.gov/pubmed/25766319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.52
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