MicroRNA-532-3p regulates mitochondrial fission through targeting apoptosis repressor with caspase recruitment domain in doxorubicin cardiotoxicity

Doxorubicin (DOX) is a wide-spectrum antitumor drug, but its clinical application is limited by its cardiotoxicity. However, the mechanisms underlying DOX-induced cardiomyopathy remain mostly unclear. Here we observed that apoptosis repressor with caspase recruitment domain (ARC) was downregulated i...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Wang, J-X, Zhang, X-J, Feng, C, Sun, T, Wang, K, Wang, Y, Zhou, L-Y, Li, P-F
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4385919/
https://ncbi.nlm.nih.gov/pubmed/25766316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.41
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