Lack of gp130 expression in hepatocytes attenuates tumor progression in the DEN model

Chronic liver inflammation is a crucial event in the development and growth of hepatocellular carcinoma (HCC). Compelling evidence has shown that interleukin-6 (IL-6)/gp130-dependent signaling has a fundamental role in liver carcinogenesis. Thus, in the present study we aimed to investigate the role...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Hatting, M, Spannbauer, M, Peng, J, Al Masaoudi, M, Sellge, G, Nevzorova, Y A, Gassler, N, Liedtke, C, Cubero, F J, Trautwein, C
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4385909/
https://ncbi.nlm.nih.gov/pubmed/25741592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.590
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