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Contractile dysfunction in muscle may underlie androgen-dependent motor dysfunction in spinal bulbar muscular atrophy
Spinal and bulbar muscular atrophy (SBMA) is characterized by progressive muscle weakness linked to a polyglutamine expansion in the androgen receptor (AR). Current evidence indicates that mutant AR causes SBMA by acting in muscle to perturb its function. However, information about how muscle functi...
Gorde:
| Argitaratua izan da: | J Appl Physiol (1985) |
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| Egile Nagusiak: | , , , , , , , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
American Physiological Society
2015
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4385878/ https://ncbi.nlm.nih.gov/pubmed/25663674 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.00886.2014 |
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