Mutation profiling of tumor DNA from plasma and tumor tissue of colorectal cancer patients with a novel, high-sensitivity multiplexed mutation detection platform

BACKROUND: Circulating tumor DNA (ctDNA) holds promise as a non-invasive means for tumor monitoring in solid malignancies. Assays with high sensitivity and multiplexed analysis of mutations are needed to enable broad application. METHODS: We developed a new assay based on sequence-specific synchrono...

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Vydáno v:Oncotarget
Hlavní autoři: Kidess, Evelyn, Heirich, Kyra, Wiggin, Matthew, Vysotskaia, Valentina, Visser, Brendan C., Marziali, Andre, Wiedenmann, Bertram, Norton, Jeffrey A., Lee, Mark, Jeffrey, Stefanie S., Poultsides, George A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2014
Témata:
Clinical Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4385870/
https://ncbi.nlm.nih.gov/pubmed/25575824
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