γ-H2AX promotes hepatocellular carcinoma angiogenesis via EGFR/HIF-1α/VEGF pathways under hypoxic condition

Hepatocellular carcinoma (HCC) is one of the most deadly cancers. Using mRNA microarray analysis, we found that H2AX decreased under hypoxic conditions. Hypoxia is an important physiological and pathological stress that induces H2AX phosphorylation (γ-H2AX), but the regulatory mechanism of γ-H2AX re...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Xiao, Heng, Tong, Rongliang, Ding, Chaofeng, Lv, Zhen, Du, Chengli, Peng, Chuanhui, Cheng, Shaobing, Xie, Haiyang, Zhou, Lin, Wu, Jian, Zheng, Shusen
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2014
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4385844/
https://ncbi.nlm.nih.gov/pubmed/25537504
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