γ-H2AX promotes hepatocellular carcinoma angiogenesis via EGFR/HIF-1α/VEGF pathways under hypoxic condition

Hepatocellular carcinoma (HCC) is one of the most deadly cancers. Using mRNA microarray analysis, we found that H2AX decreased under hypoxic conditions. Hypoxia is an important physiological and pathological stress that induces H2AX phosphorylation (γ-H2AX), but the regulatory mechanism of γ-H2AX re...

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Vydáno v:Oncotarget
Hlavní autoři: Xiao, Heng, Tong, Rongliang, Ding, Chaofeng, Lv, Zhen, Du, Chengli, Peng, Chuanhui, Cheng, Shaobing, Xie, Haiyang, Zhou, Lin, Wu, Jian, Zheng, Shusen
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2014
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4385844/
https://ncbi.nlm.nih.gov/pubmed/25537504
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