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Using engineered endonucleases to create knockout and knockin zebrafish models

Over the last few years, the technology to create targeted knockout and knockin zebrafish animals has exploded. We have gained the ability to create targeted knockouts through the use of zinc finger nucleases (ZFNs), transcription activator-like effector nucleases (TALENs) and clustered regularly in...

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Bibliographic Details
Published in:Methods Mol Biol
Main Authors: Bedell, Victoria M., Ekker, Stephen C.
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4385738/
https://ncbi.nlm.nih.gov/pubmed/25408414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-1862-1_17
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