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Selective agonists of somatostatin receptor subtype 1 or 2 injected peripherally induce antihyperalgesic effect in two models of visceral hypersensitivity in mice

Somatostatin interacts with 5 G-protein-coupled receptor (sst(1–5)). Octreotide, a stable sst(2≫3≥5) agonist, octreotide, exerts a visceral anti-hyperalgesic effect in experimental and clinical studies. Little is known on the receptor subtypes involved. We investigated the influence of the stable ss...

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Detalles Bibliográficos
Publicado en:Peptides
Main Authors: Mulak, Agata, Larauche, Muriel, Biraud, Mandy, Million, Mulugeta, Rivier, Jean, Taché, Yvette
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4385413/
https://ncbi.nlm.nih.gov/pubmed/25451334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.peptides.2014.10.013
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