Biodistribution and in Vivo Toxicity of Aptamer-Loaded Gold Nanostars

This paper reports an in vivo evaluation of toxicology and biodistribution of a highly anisotropic Au nanoconstruct composed of a gold nanostar (AuNS) core and a ligand shell of a G-quadruplex DNA aptamer AS1411 (Apt) supporting both targeting and therapy capabilities. We examined the toxicity of th...

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Udgivet i:Nanomedicine
Main Authors: Dam, Duncan Hieu M., Culver, Kayla S.B., Kandela, Irawati, Lee, Raymond C., Chandra, Kavita, Lee, Hyojin, Mantis, Christine, Ugolkov, Andrey, Mazar, Andrew P., Odom, Teri W.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4385396/
https://ncbi.nlm.nih.gov/pubmed/25461281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2014.10.005
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