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Epilepsy in Succinic Semialdehyde Dehydrogenase Deficiency, a Disorder of GABA Metabolism

OBJECTIVES: Succinic semialdehyde dehydrogenase (SSADH) deficiency is a gamma-aminobutyric acid (GABA) degradative defect. Epilepsy affects half of patients. The murine model is associated with a transition from absence to convulsive seizures in the third week, with fatal status epilepticus. METHODS...

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Detalhes bibliográficos
Publicado no:Brain Dev
Main Authors: Pearl, Phillip L., Shukla, Lovy, Theodore, William H., Jakobs, Cornelis, Gibson, K. Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4385391/
https://ncbi.nlm.nih.gov/pubmed/21664777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.braindev.2011.04.013
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