Granulocyte colony-stimulating factor receptor signaling involves the formation of a three-component complex with Lyn and Syk protein-tyrosine kinases.

Granulocyte colony-stimulating factor (G-CSF) is a glycoprotein that critically regulates the viability, proliferation, and differentiation of granulocytic precursors and the function of neutrophils by signaling through its receptor. Cloning of the human G-CSF receptor (G-CSFR) cDNA has demonstrated...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Corey, S J, Burkhardt, A L, Bolen, J B, Geahlen, R L, Tkatch, L S, Tweardy, D J
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1994
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC43852/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8197119/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.11.4683
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