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Cloning, expression and purification of Mycobacterium tuberculosis ESAT-6 and CFP-10 antigens

BACKGROUND AND OBJECTIVES: ESAT-6 (6-kDaearly secretory antigenic target) and CFP-10 (10-kDa culture filtrate protein) have been described as dominant antigens recognized by T-cells and considered as virulence factors in Mycobacterium tuberculosis. The aim of this study was to clone, express and pur...

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Bibliografiske detaljer
Udgivet i:Iran J Microbiol
Main Authors: Mahmoudi, Shima, Mamishi, Setareh, Ghazi, Mona, Hosseinpour Sadeghi, Reihaneh, Pourakbari, Babak
Format: Artigo
Sprog:Inglês
Udgivet: Tehran University of Medical Sciences 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4385163/
https://ncbi.nlm.nih.gov/pubmed/25848507
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