Fluid shear stress induces a biphasic response of human monocyte chemotactic protein 1 gene expression in vascular endothelium.

The focal distribution of atherosclerotic lesions in the arterial tree is related to the local shear stress generated by blood flow, but the molecular basis of the atherogenic response of endothelial cells in these lesion-prone areas is still unclear. We report that shear stress mediates a biphasic...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Shyy, Y J, Hsieh, H J, Usami, S, Chien, S
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1994
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC43851/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8197118/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.11.4678
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